Antonio Sebastiano Bettini was an Italian painter of the 18th century. He was the son of an architect and was initially trained in Florence by Giovanni Camillo Sagrestani and Ottavio Dandini. He was financially supported by the Salviati family, who sent him to Rome in 1737, where he completed his training at the school of Sebastiani Conca. Only a few of his works have survived, however, documentary evidence has been preserved. For the Palazzo Salviati in Florence he painted mythological allegories and some religious paintings that have not survived. His works for churches in Florence also no longer exist today.